New perch for the winged helix

Authors
Wolberger, C Campbell, R
Citation
C. Wolberger et R. Campbell, New perch for the winged helix, NAT ST BIOL, 7(4), 2000, pp. 261-262
Citations number
20
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NATURE STRUCTURAL BIOLOGY
ISSN journal
10728368 → ACNP
Volume
7
Issue
4
Year of publication
2000
Pages
261 - 262
Database
ISI
SICI code
1072-8368(200004)7:4<261:NPFTWH>2.0.ZU;2-2
Abstract
The human transcription factor RFX1, is found to belong to the winged-helix family of DNA binding proteins, despite an absence of significant sequence similarity. Even more surprising is the Very different mode of DNA binding as compared with previously characterized winged-helix proteins that bind to B-form DNA.