Research on stress tends to support an adverse effect on pregnancy outcomes
, and suggests that the impact of these stressors is modified by social cla
ss and/or race. This study explicitly examined social factors such as exper
iences of discrimination, either racial or sexual, and neighbourhood crime
as predictors of stress. We also examined cortisol and stress as predictors
of blood pressure. A subsample of 94 African-American pregnant women, aged
18-39 years, who were enrolled in a longitudinal study of pregnancy and ex
posure to lead in the environment were used in this analysis. The women wer
e patients at an obstetrics clinic at Magee Women's Hospital in Pittsburgh,
PA, USA. Younger age, higher income, lower education and experiences of di
scrimination, both racial and sexual, were related to greater perceived str
ess; however, life events were not related to perceived stress. Higher inco
me and urinary cortisol adjusted for creatinine were related to systolic bl
ood pressure after the 36th week. As a body of evidence suggests that stres
s can have deleterious effects in both pregnant and non-pregnant women, fut
ure research should examine these forms of discrimination, especially racia
l discrimination, as a possible reason for the disparity in adverse pregnan
cy outcomes between African-American and white women.