Prevalence of osteoporosis risk factors and treatment among women aged 50 years and older

Citation
Jk. Kirk et al., Prevalence of osteoporosis risk factors and treatment among women aged 50 years and older, PHARMACOTHE, 20(4), 2000, pp. 405-409
Citations number
13
Categorie Soggetti
Pharmacology
Journal title
PHARMACOTHERAPY
ISSN journal
02770008 → ACNP
Volume
20
Issue
4
Year of publication
2000
Pages
405 - 409
Database
ISI
SICI code
0277-0008(200004)20:4<405:POORFA>2.0.ZU;2-2
Abstract
We conducted a cross-sectional, retrospective review to evaluate screening, diagnosis, and treatment of 359 women aged 50 years or older at risk for o steoporosis in a large primary care practice. Records randomly selected fro m a computerized database were reviewed for drug history, age, height, weig ht, and osteoporosis-related diagnoses, symptoms, and risk factors. Among t he 389 women, 255 (65.5%) were receiving bone-preserving treatment (247 est rogen replacement exclusively). Most (70.4%) were white, with an average ag e of 61 years, and an average of 3.3 risk factors for osteoporosis. Risk fa ctors were postmenopausal status 94%, age 65 years or older 53%, hysterecto my 39%, cigarette smoking 33%, and physical inactivity 30%. By logistic reg ression, the only positive predictor of antiresorptive therapy was hysterec tomy (adjusted odds ratio [AOR] 2.52, 95% confidence interval [CI] 1.54-4.1 4). Negative predictors were, physical inactivity (AOR 0.44, 95% CI 0.25-0. 71), rheumatoid arthritis (AOR 0.31, 95% CI 0.12-0.79), and age 65 years an d older (AOR 0.54, 95% CI 0.34-0.86). Controlling for age, women with four or more risk factors were 62% less likely to be receiving antiresorptive tr eatment (AOR 0.38, 95% CI 0.23-0.64) than those with fewer risk factors.