Objectives: We hypothesized that people in Morocco are more irritable durin
g the month of Ramadan than during the rest of the year. Our objectives wer
e to measure irritability in fasting Muslims during the month of Ramadan, t
o describe its various modes of expression, and to examine risk factors fur
this irritability. Methods and Subjects: We studied 100 healthy volunteers
during the month of Ramadan for two successive years (1994 and 1995). All
subjects were male (mean age, 32 +/- 5.8 years), and 51% of them were smoke
rs. Irritability was assessed over a g-week period (before, four times duri
ng, and after the end of Ramadan). We assessed both subjective (visual anal
og scale) and objective irritability. We also recorded the consumption of p
sychostimulants, duration of sleep, and anxiety level as measured by the Ha
milton Anxiety Scale. Results: Irritability was significantly higher in smo
kers than in nonsmokers before the beginning of Ramadan. It was higher in b
oth groups during the Ramadan month. Irritability increased continuously du
ring Ramadan and reached its peak at the end of the month. Consumption of p
sychostimulants (coffee and tea) and anxiety level followed the same patter
n. Smokers and nonsmokers had a similar pattern of irritability over time,
but irritability increased more in smokers than in nonsmokers.