Effect of weak (dispersion) intermolecular interactions on physical properties of organic compounds

Data on the properties of organic compounds are collected and comparative a nalysis of the data is performed. The dataset contains information on prope rties sensitive to structural variations, such as boiling point (bp), melti ng point (mp), and molecular packing factor (K-p), for specially selected c omparative series of compounds including homologous series. These comparati ve series of ca. 1000 organic compounds include saturated, unsaturated, lin ear, branched, and cyclic hydrocarbons with only weak sites of intermolecul ar interaction of dispersion type. Regular trends and features of intermole cular interactions in hydrocarbons of various classes were revealed, indica ting that the intensity of intermolecular interactions is the principal cha racteristic that defines bp, mp, and K-p of a hydrocarbon. The molecular sy mmetry and shape (set of conformational states) also contributes to formati on of systems of intermolecular interactions. These factors affect the dens ity and order in molecular packing of organic compounds with the dispersion type of intermolecular interactions.