F. Dehmel et al., Preparation of new magnesiated functionalized imidazoles and antipyrines via an iodine-magnesium exchange, SYNLETT, (3), 2000, pp. 345-346
The iodine-magnesium exchange using i-PrMgBr allows the preparation of magn
esiated 3-pyrazolin-5-ones (antipyrines) and functionalized imidazoles whic
h after reaction with various electrophiles afford polyfunctional 5-membere
d heterocycles.