A one-pot synthesis of tetrahydroisoquinolonic acids from aldehydes and amines in trimethylorthoformate

Authors
Yu, NF Poulain, R Gesquiere, JC
Citation
Nf. Yu et al., A one-pot synthesis of tetrahydroisoquinolonic acids from aldehydes and amines in trimethylorthoformate, SYNLETT, (3), 2000, pp. 355-356
Citations number
6
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
3
Year of publication
2000
Pages
355 - 356
Database
ISI
SICI code
0936-5214(200003):3<355:AOSOTA>2.0.ZU;2-B
Abstract
Tetrahydroisoquinolonic acids are synthesized in the presence of excess tri methyl orthoformate by a one-pot procedure directly from the corresponding amines, aldehydes and homophthalic anhydride.