Observations on the use of triphenylphosphonium bromide as a mild and quantifiable source of hydrogen bromide for chemoselective ring opening of epoxides to bromohydrins

Authors
Afonso, CAM Vieira, NML Motherwell, WB
Citation
Cam. Afonso et al., Observations on the use of triphenylphosphonium bromide as a mild and quantifiable source of hydrogen bromide for chemoselective ring opening of epoxides to bromohydrins, SYNLETT, (3), 2000, pp. 382-384
Citations number
12
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
3
Year of publication
2000
Pages
382 - 384
Database
ISI
SICI code
0936-5214(200003):3<382:OOTUOT>2.0.ZU;2-V
Abstract
The chemoselective ring opening of epoxides to bromohydrins in the presence of ketal, benzyloxymethoxy and trimethylsilyl ether functionality using tr iphenylphosphonium bromide is described. The preparation of a polymer suppo rted variant is also reported.