Observations on the use of triphenylphosphonium bromide as a mild and quantifiable source of hydrogen bromide for chemoselective ring opening of epoxides to bromohydrins
Cam. Afonso et al., Observations on the use of triphenylphosphonium bromide as a mild and quantifiable source of hydrogen bromide for chemoselective ring opening of epoxides to bromohydrins, SYNLETT, (3), 2000, pp. 382-384
The chemoselective ring opening of epoxides to bromohydrins in the presence
of ketal, benzyloxymethoxy and trimethylsilyl ether functionality using tr
iphenylphosphonium bromide is described. The preparation of a polymer suppo
rted variant is also reported.