G. Vidari et al., Enantioselective synthesis of each stereoisomer of the pyranoid linalool oxides: the geraniol route, TETRAHEDR-A, 11(4), 2000, pp. 981-989
Each of the four enantiomerically pure tetrahydropyran linalool oxides was
synthesized by an acid-catalyzed cyclization of an appropriate epoxy-alcoho
l obtained by consecutive Sharpless dihydroxylation (AD) and epoxidation (A
E) reactions of geraniol derivatives. An interesting example of double asym
metric induction was observed during the AE of a bis(homoallylic) N-naphthy
lcarbammae. (C) 2000 Elsevier Science Ltd. All rights reserved.