Aa. Leis et J. Fratkin, CHONDROSARCOMA OF THE SPINE AND THYROID-CARCINOMA FOLLOWING RADIATION-THERAPY FOR HODGKINS LYMPHOMA, Neurology, 48(6), 1997, pp. 1710-1712
Second malignant neoplasms are an infrequent but well-documented seque
lae of radiation therapy for childhood cancer. We report a 34-year-old
man with chondrosarcoma of the spine and thyroid carcinoma diagnosed
24 years after radiation therapy for Hodgkin's lymphoma. Both tumors a
rose in the previously irradiated field and were not detected until th
e patient presented with paraplegia. The propensity of these neoplasms
to arise in the previously irradiated field warrants physicians to be
alert to any manifestations arising in this anatomic area.