ANTIMUSCLE AND ANTI-CNS CIRCULATING ANTIBODIES IN CHRONIC-FATIGUE-SYNDROME

Chronic fatigue syndrome (CFS) patients suffer from disabling physical and mental fatigue. Circulating autoimmune antibodies may produce sym ptoms of muscular fatigue by reacting with acetylcholine receptors or calcium binding channels. They can also produce mental status changes by reacting with central nervous system (CNS) antigens. We thoroughly investigated the presence of circulating antimuscle and anti-CNS antib odies in 10 CFS patients and 10 controls. We were unable to detect any pathogenic antibodies.