Background: depression is common but under-diagnosed in nursing-home reside
nts. There is a need for a standardized screening instrument which incorpor
ates daily observations of nursing-home staff.
Aim: to develop and validate a screening instrument for depression using it
ems from the Minimum Data Set of the Resident Assessment Instrument.
Methods: we conducted semi-structured interviews with 108 residents from tw
o nursing homes to obtain depression ratings using the 17-item Hamilton Dep
ression Rating Scale and the Cornell Scale for Depression in Dementia. Nurs
ing staff completed Minimum Data Set assessments. In a randomly assigned de
rivation sample (n = 81), we identified Minimum Data Set mood items that we
re correlated (P < 0.05) with Hamilton and Cornell ratings. These items wer
e factored using an oblique rotation to yield five conceptually distinct fa
ctors. Using linear regression, each set of factored items was regressed ag
ainst Hamilton and Cornell ratings to identify a core set of seven Minimum
Data Set mood items which comprise the Minimum Data Set Depression Rating S
cale. We then tested the performance of the Minimum Data Set Depression Rat
ing Scale against accepted cut-offs and psychiatric diagnoses.
Results: a cutpoint score of 3 on the Minimum Data Set Depression Rating Sc
ale maximized sensitivity (94% for Hamilton, 78% for Cornell) with minimal
loss of specificity (72% for Hamilton, 77% for Cornell) when tested against
cut-offs for mild to moderate depression in the derivation sample. Results
were similar in the validation sample. When tested against diagnoses of ma
jor or non-major depression in a subset of 82 subjects, sensitivity was 91%
and specificity was 69%, Performance compared favourably with the 15-item
Geriatric Depression Scale.
Conclusion: items from the Minimum Data Set can be organized to screen for
depression in nursing-home residents. Further testing of the instrument is
now needed.