Three-dimensional helical computed tomographic angiography in neonates andinfants with complex congenital heart disease

Background For the clinical management of patients with complex congenital heart disease (CHD), accurate evaluation of their morphologic conditions is critical. Three-dimensional (3D) helical computed tomography (CT) angiogra phy has been used to assess the vascular system in adult patients; the indi cation for complex CHD, especially in the neonatal period, has nor yet been defined. Therefore the purposes of our study were to determine the quality and limitations of current 3D helical CT angiography for neonates and infa nts with complex CHD and to assess the clinical utility of this technique. Methods and Results 3D helical CT angiography was performed in 17 patients with various types of complex CHD. Their median age was 41 days (range 3 da ys to 9 months), and mean body weight was 3.6 kg (range 2.2 to 8.5 kg). An 3D images were produced with the 3D reconstruction algorithm of shaded-surf ace display. Oral sedation was required in only 4 infants during the proced ure. 3D helical CT angiography clearly demonstrated the shape and spatial r elation of great arteries, proximal branch pulmonary arteries, anomalous pu lmonary venous connections, the potent ductus arteriosus, and a shunt. The 3D information of extracardiac morphologic characteristics and 3D anatomic relation of each extracardiac structure were easily recognized by this imag ing process. However, intracardiac structure could not be visualized becaus e of blurred and/or unclear edges of the ventricular wall caused by respira tory movement. Conclusions 3D helical CT angiography represents an important additional di agnostic tool and may become an alternative method to angiography or other noninvasive techniques used in the evaluation of extracardiac anomalies in neonates and infants with complex CHD.