The components of carbonless copy paper (CCP) and the chemistry involved in
its manufacture are reviewed. Claims that the routine use of CCP can cause
health problems ranging from skin, eye, and lung irritation to severe head
aches and neurological damage are described; yet no definitive studies have
been conducted that show correlation between CCP use and these symptoms. T
he toxicological properties of CCP components, many of them precursors to t
he dye-containing microcapsules or dye solvents that may be causing these p
roblems, are discussed. Recommendations for the minimization of possible ph
ysiological reactions to CCP include reduction of usage time; use of the CC
P in a well-ventilated area; storing large quantities of CCP, both new or a
rchived, away from work area; and the practice good hand hygiene.