Among the large variety of cerebrovascular syndromes, carotid artery dissec
tions remain often under-recognized. Many patients present with minor or tr
ansient symptoms, some with local pain only, and some are asymptomatic. A u
seful rule is that the coincidence of any local pain in neck or face with a
n ipsilateral Homer's syndrome preceding transient or persistent retinal or
cerebral ischemic symptoms should alert physicians-notably those treating
emergencies-to rule out an underlying dissection of the ipsilateral carotid
artery. In most cases the extracranial part of the carotid artery is affec
ted; therefore, this review will focus on this main subgroup of patients. W
e review the pathological anatomy, as well as possible underlying causes, c
linical features, diagnostic tools, differential diagnosis, treatment optio
ns, and outcome data.