P. Benedettipanici et al., A RANDOMIZED STUDY COMPARING RETROPERITONEAL DRAINAGE WITH NO DRAINAGE AFTER LYMPHADENECTOMY IN GYNECOLOGIC MALIGNANCIES, Gynecologic oncology, 65(3), 1997, pp. 478-482
Objective: To evaluate the clinical effectiveness of retroperitoneal d
rainage following lymphadenectomy in gynecologic surgery. Methods: One
hundred thirty-seven consecutive patients undergoing systematic lymph
adenectomy for gynecologic malignancies were randomized to receive (Gr
oup A, 68) or not (Group B, 69) retroperitoneal drainage. The pelvic p
eritoneum and the paracolic gutters were not sutured after node dissec
tion. Perioperative data and complications were recorded. Results: Cli
nical and surgical parameters were comparable in the two groups. Posto
perative hospital stay was significantly shorter in Group B (P < 0.001
), whereas the complication rate was significantly higher in Group A (
P = 0.01). This was mainly due to a significant increase in lymphocyst
and lymphocyst-related morbidity. Sonographic monitoring for lymphocy
st showed free abdominal fluid in 18% of drained and 36% of not-draine
d patients (P = 0.03). Symptomatic ascites developed in 2 drained (3%)
and 3 not-drained (4%) patients (NS), respectively. Conclusions: Prop
hylactic drainage of the retroperitoneum seems to increase lymphadenec
tomy-related morbidity and postoperative stay. Therefore, routine drai
nage following lymphadenectomy seems to be no longer indicated when th
e retroperitoneum is left open. (C) 1997 Academic Press.