Traditionally, acquired forms of nystagmus have been classified in descript
ive terms based on their clinical features and recorded waveforms. In the p
ast 20 years, the mechanisms of several major forms of nystagmus have been
elucidated; animal and mathematical models for these ocular oscillations ha
ve been developed. These advances, which owe much to modem anatomical, phys
iological, and pharmacological techniques, have enhanced the diagnostic val
ue of nystagmus and provide: the basis for developing rational therapy.