The amount of papers in the literature describing reactions catalyzed by en
zymes and microorganisms as a method for obtaining enantiomerically pure co
mpounds is increasing considerably. The usefulness of these biocatalysts in
organic chemistry is now well documented and has greatly increased in the
last decade. This review de scribes the most relevant recent papers on the
subject and also some very successful applications of the enzymes and micro
organisms as biocatalysts in synthetic organic chemistry from the 1996 lite
rature up till now.