Over a 3-year period 23 patients with malignant superior vena cava obstruct
ion were referred for interventional management. They underwent repeat loca
lized central venography and deployment of self-expanding Wallstents. All p
atients (age range 26-89 years) were approached by the subclavian route usi
ng 29 stents. The stent was used to exclude thrombus in the contralateral b
rachiocephalic vein in five patients and histologic information was availab
le in all patients. Retrospective analysis of the clinical records was used
to assess symptom-free survival and symptom recurrence.
All patients reported an improvement in symptoms within 24hr of the procedu
re. There was 100% technical success. Primary clinical success was achieved
in 19 of 23 patients followed-up to their death with no symptom recurrence
(range 1-34, mean 15 weeks). In four patients symptoms recurred but only o
ne patient was referred for re-intervention, which was successful. Complica
tions included single cases of early post-stent rethrombosis, distal slip o
n deployment, and distal slip on balloon dilatation. There were no puncture
-related complications.