Low whole blood glutathione levels in pregnancies complicated by preeclampsia and diabetes

Authors
Kharb, S
Citation
S. Kharb, Low whole blood glutathione levels in pregnancies complicated by preeclampsia and diabetes, CLIN CHIM A, 294(1-2), 2000, pp. 179-183
Citations number
16
Categorie Soggetti
Medical Research Diagnosis & Treatment
Journal title
CLINICA CHIMICA ACTA
ISSN journal
00098981 → ACNP
Volume
294
Issue
1-2
Year of publication
2000
Pages
179 - 183
Database
ISI
SICI code
0009-8981(200004)294:1-2<179:LWBGLI>2.0.ZU;2-K
Abstract
Nineteen pregnancies with preeclampsia, 16 with diabetic preeclampsia and 2 9 control pregnancies were analyzed with regards to maternal total glutathi one. In preeclampsia, maternal total glutathione levels were lower than in normal pregnancy (P < 0.001). Also, diabetic preeclamptics showed low total glutathione levels as compared to preeclampsia (P < 0.05) and control (P < 0.001). These findings indicate decreased detoxificating or free radical s cavenging capacity in pregnancies complicated by preeclampsia and diabetes. (C) 2000 Elsevier Science B.V. All rights reserved.