A 71-year-old slender, previously healthy man was admitted to the authors'
institution because of a huge painless mass in his left scapular area. Phys
ical examination revealed a second soft tissue mass in his right scapular r
egion and a third soft tissue mass in the anterior side of his right should
er. Surgical treatment including marginal resection of the second and third
small masses followed by wide local resection of the huge tumor was perfor
med. Histologic examination showed that the first mass was a well different
iated lipomalike liposarcoma, whereas the second and third lesions were ide
ntified as intramuscular lipomas, A review of the literature showed two cas
es of retroperitoneal liposarcoma associated with multiple subcutaneous lip
omas and two cases of liposarcoma involving an extremity associated with mu
ltiple subcutaneous lipomas. There is no previous report in which intramusc
ular liposarcoma was associated with multiple intramuscular lipomas.