Numerous epidemiological studies have linked tobacco use with a wide variet
y of diseases. Strong government-supported anti-smoking campaigns have decr
eased the prevalence of smoking in many developed countries, including the
United States. However, it remains a major public health pariah. In develop
ing countries, such as China, cigarette smoking and other forms of tobacco
use continue to increase. If unchecked this will eventually lead to 10 mill
ion deaths per year worldwide. Even in the United States, the prevalence of
smoking is rising in crucial population groups such as adolescents. Recent
advances have made physicians more able to help patients quit smoking but
organized campaigns must be further strengthened to prevent the initiation
of tobacco use, especially in the young.