Transgenic animals with altered high-density lipoprotein composition and functions

Authors
Kalopissis, AD Chambaz, J
Citation
Ad. Kalopissis et J. Chambaz, Transgenic animals with altered high-density lipoprotein composition and functions, CURR OP LIP, 11(2), 2000, pp. 149-153
Citations number
54
Categorie Soggetti
Cardiovascular & Hematology Research
Journal title
CURRENT OPINION IN LIPIDOLOGY
ISSN journal
09579672 → ACNP
Volume
11
Issue
2
Year of publication
2000
Pages
149 - 153
Database
ISI
SICI code
0957-9672(200004)11:2<149:TAWAHL>2.0.ZU;2-9
Abstract
Our understanding of HDL metabolism in vivo has greatly advanced from studi es with transgenic animals, Interactions between HDL apolipoproteins, trans fer proteins, lipolytic enzymes and receptors modulate HDL size, particle n umber and fractional catabolic rate. The protective effect of HDL on athero sclerosis depends on the combined actions of HDL proteins and the metabolis m of apo B-lipoproteins. Curr Opin Lipidol 11:149-153. (C) 2000 Lippincott Williams & Wilkins.