Perinatal differential diagnosis of cystic kidney disease and urinary tract obstruction: anatomic pathologic, ultrasonographic and genetic findings

According to the classification of Osathanondh and Potter of cystic kidney diseases an antenatal differential diagnosis is presented, which is based o n the anatomic pathologic, ultrasonographic and genetic findings. Since the ultrasound evaluation influences the obstetric and neonatal management, ea ch second and third trimester sonography should consider the most common ma lformations in pediatric autopsies. The autosomal recessive polycystic kidn ey disease (ARPK), autosomal dominant polycystic kidney disease (ADPK), mul ticystic renal dysplasia, obstructive multicystic kidneys and cystic renal malformations found in other syndromes with genetic linkage are discussed i n this review. (C) 2000 Elsevier Science ireland Ltd. All rights reserved.