Lethal fetal renal anomalies and obstetric outcome

Citation
Mw. Carpenter et al., Lethal fetal renal anomalies and obstetric outcome, EUR J OB GY, 89(2), 2000, pp. 149-152
Citations number
14
Categorie Soggetti
Reproductive Medicine
Journal title
EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY
ISSN journal
03012115 → ACNP
Volume
89
Issue
2
Year of publication
2000
Pages
149 - 152
Database
ISI
SICI code
0301-2115(200004)89:2<149:LFRAAO>2.0.ZU;2-L
Abstract
The incidence of prenatal and intrapartum complications was examined among 33 pregnancies complicated by lethal fetal renal abnormalities (cases) and compared to 200 contemporaneous control pregnancies (controls) by retrospec tive record review. Cases experienced higher rates of antepartum bleeding ( 2946 vs. 6%, p<0.0001) stillbirth (15% vs. 0%, p<0.0001), preterm birth (34 .3+/-4.1 vs. 39.7+/-1.8, p<0.0001) and breech presentation (48% vs. 4%, p<0 .0001). Twenty-six of 33 cases had lung weights less than or equal to first centile. Primary cesarean section occurred more frequently in cases than i n controls (48% vs. 9%, p<0.0001). Knowledge of poor fetal prognosis alone did not appear to influence obstetrical management. We conclude that timely consultation with sonologist and neonatologist and patient counseling may avoid unnecessary obstetrical intervention when pregnancy complications occ ur. Pregnancies complicated by lethal fetal renal abnormalities have higher rates of ante- and intrapartum complications leading to frequent abdominal delivery. This suggests that accurate predictive markers for lethal fetal renal disease may reduce ineffective obstetric intervention. (C) 2000 Elsev ier Science Ireland Ltd. All rights reserved.