Modeling molecular motors as folding-unfolding cycles

Citation
A. Hansen et al., Modeling molecular motors as folding-unfolding cycles, EUROPH LETT, 50(1), 2000, pp. 120-124
Citations number
15
Categorie Soggetti
Physics
Journal title
EUROPHYSICS LETTERS
ISSN journal
02955075 → ACNP
Volume
50
Issue
1
Year of publication
2000
Pages
120 - 124
Database
ISI
SICI code
0295-5075(200004)50:1<120:MMMAFC>2.0.ZU;2-P
Abstract
We propose a model for motor proteins based on a hierarchical Hamiltonian t hat we have previously introduced to describe protein folding. The proposed motor model has a power stroke of high efficiency and an overall dynamics that is consistent with a linear load-velocity response. The model suggests a connection between folding and function of allosteric proteins.