Pesticides occupy a unique position among chemicals found in drinking water
, since they are deliberately used to control pests in agriculture and publ
ic health. They comprise a variety of compounds of various chemical propert
ies (many of which being persistent in the environment), toxic potential, a
nd mechanism of action. Safety assessment for drinking water is conducted b
y allocating health-based guidelines for exposure through this environmenta
l medium. The tolerable daily intake (TDI) approach is used by WHO in the c
ase of pesticides with assumed thresholds of effect, while low-dose extrapo
lation is used in the case of non-threshold carcinogens. Risk management, h
owever, can also be based on the precautionary principle. Risk assessment e
valuates the risk emanating from a given exposure on the basis of all avail
able data. (C) 2000 Elsevier Science Ltd. All rights reserved.