An apparently unique intramural uterine lesion is described for which we pr
opose the name adenolipoleiomyoma. On gross examination, a well-circumscrib
ed white intramural mass contained focal fatty areas. Histology showed the
mass to be composed of smooth muscle, adipose tissue, and endometrial, endo
cervical, and tubal type glands. The endometrial glands were surrounded by
typical endometrial stroma. There was no evidence of adenomyosis in the ute
rus outside the lesion. This is only the second report of such a lesion wit
hin the uterus and the first with an intramural location. We believe it to
be a benign hamartomatous lesion.