Increase in O-2 delivery with hyperoxia does not increase O-2 uptake in tetanically contracting dog muscle

Authors
Kohzuki, H Sakata, S Ohga, Y Misawa, H Kishi, T Takaki, M
Citation
H. Kohzuki et al., Increase in O-2 delivery with hyperoxia does not increase O-2 uptake in tetanically contracting dog muscle, JPN J PHYSL, 50(1), 2000, pp. 167-169
Citations number
16
Categorie Soggetti
Physiology
Journal title
JAPANESE JOURNAL OF PHYSIOLOGY
ISSN journal
0021521X → ACNP
Volume
50
Issue
1
Year of publication
2000
Pages
167 - 169
Database
ISI
SICI code
0021-521X(200002)50:1<167:IIODWH>2.0.ZU;2-Z
Abstract
We investigated the influence of hyperoxia on O-2 uptake in tetanically con tracting canine gastrocnemius. Hyperoxia showed neither increase in O-2 upt ake nor decrease in lactate release, irrespective of increased O-2 Supply, venous PO2 and vascular resistance, as compared to normoxia, suggesting tha t hyperoxia decreases O-2 diffusion conductance and/or effective O-2 supply probably due to arteriovenous O-2 diffusion shunt.