Two year results: Sharp versus rounded optic edges on silicone lenses

Purpose: To evaluate the role of optic edge design of 2 silicone intraocula r lenses (IOL) in 2 year clinical results. Setting: Department of Ophthalmology, University of Vienna, Medical School, Allgemeines Krankenhaus, Austria. Methods: In this comparative clinical study, 50 eyes had phacoemulsificatio n and implantation of a high-refractive 3-piece silicone IOL with sharp opt ic edges (CeeOn(TM) model 911F) (n = 25) or a 3-piece silicone lens with ro unded optic edges (CeeOn(TM) model 920) (n = 25). Biomicroscopic findings, including those of specular microscopic examination of the anterior lens su rface, were documented and the results analyzed. Results: After 2 years, a significant between-group difference in posterior capsule opacification (PCO) but not in anterior capsule alterations was ob served. Behind all CeeOn 911F sharp-edge IOLs, the capsule remained clear; in 2 of 23 capsules behind the CeeOn 920 rounded-edge, a neodymium: YAG las er capsulotomy had to be performed for dense central fibrotic PCO. Seven of 21 of the remaining eyes had first-degree central fibrotic PCO, 14 of 23 h ad peripheral mixed fibrotic and slender Elschnig pearl PCO, and 8 of 23 ha d second-degree peripheral PCO. Specular microscopic findings did not diffe r between the 2 groups. No severe IOL decentration occurred in any eye; 25% in the sharp-edge group and 40% in the rounded-edge group had minimal dece ntration. Conclusion: The silicone IOL with the sharp optic edge design was associate d with significantly reduced PCO 2 years postoperatively. J Cataract Refrac t Surg 2000; 26:566-570 (C) 2000 ASCRS and ESCRS.