Efficient stereoconservative syntheses of 4,4-difluoro-2-hydroxybutyric acids from (S)- and (R)-malic and (S)- and (R)-citramalic acid

Authors
Burger, K Lange, T Pires, R
Citation
K. Burger et al., Efficient stereoconservative syntheses of 4,4-difluoro-2-hydroxybutyric acids from (S)- and (R)-malic and (S)- and (R)-citramalic acid, J FLUORINE, 102(1-2), 2000, pp. 317-321
Citations number
29
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
JOURNAL OF FLUORINE CHEMISTRY
ISSN journal
00221139 → ACNP
Volume
102
Issue
1-2
Year of publication
2000
Pages
317 - 321
Database
ISI
SICI code
0022-1139(200003)102:1-2<317:ESSO4A>2.0.ZU;2-R
Abstract
A preparative simple stereoconservative synthesis of homochiral 4,4-difluor o-2-hydroxybutyric acid and 4,4-difluoro-2-hydroxy-2-methylbutyric acid usi ng hexafluoroacetone as protecting and activating agent is described. (C) 2 000 Elsevier Science S.A. All rights reserved.