Middle meatal samples were obtained from 52 carefully selected healthy adul
ts. In 75 per cent of the test subjects bacterial organisms were cultured.
However, growth was often poor and the predominant species suggest a commen
sal flora: coagulase-negative staphylococci were retrieved from 35 per cent
, Corynebacterium sp. from 23 per cent and Staphyloccus aureus from eight p
er cent of the adults.
These data are very different from those previously obtained among children
where - even in the absence of obvious ENT pathology - the most frequently
cultured organisms were typical sinusitis pathogens: Haemophilus influenza
e present in 40 per cent, Moraxella catarrhalis in 34 per cent and Streptoc
occus pneumoniae in 50 per cent of children. Furthermore, Streptococcus vir
idans and Neisseria sp., both organisms that might be able to inhibit colon
ization by some of the pathogens and found commonly among children, are vir
tually absent in healthy adults.