M. Pellecchia et al., Magnetization transfer via residual dipolar couplings: Application to proton-proton correlations in partially aligned proteins, J MAGN RES, 143(2), 2000, pp. 435-439
A novel three-dimensional NMR experiment is reported that allows the observ
ation of correlations between amide and other protons via residual dipolar
couplings in partially oriented proteins. The experiment is designed to per
mit quantitative measurement of the magnitude of proton-proton residual dip
olar couplings in larger molecules and at higher degree of alignments. The
observed couplings contain data valuable for protein resonance assignment,
local protein structure refinement, and determination of low-resolution pro
tein folds. (C) 2000 Academic Press.