Paraneoplastic cerebellar degeneration and Horner syndrome: Association oftwo uncommon findings in a child with Hodgkin disease

Citation
S. Emir et al., Paraneoplastic cerebellar degeneration and Horner syndrome: Association oftwo uncommon findings in a child with Hodgkin disease, J PED H ONC, 22(2), 2000, pp. 158-161
Citations number
22
Categorie Soggetti
Pediatrics
Journal title
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
ISSN journal
10774114 → ACNP
Volume
22
Issue
2
Year of publication
2000
Pages
158 - 161
Database
ISI
SICI code
1077-4114(200003/04)22:2<158:PCDAHS>2.0.ZU;2-G
Abstract
An 11-year-old boy admitted with a right cervical mass was found to have Ho dgkin disease. On admission, he also had right Horner syndrome and severe c erebellar ataxia. Cranial MRI revealed marked cerebellar atrophy. He was tr eated with chemotherapy consisting of doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD), in addition to radiotherapy. Three months after ini tiation of therapy, he had a partial remission of tumor. Neurologic symptom s improved dramatically after chemotherapy started. Hodgkin disease should be included in the differential diagnosis of children with cerebellar findi ngs and Horner syndrome.