Sildenafil for psychotropic-induced sexual dysfunction in 31 women and 61 men

Ninety-two outpatients (32 women, 61 men) who were treated with oral silden afil for psychotropic-induced sexual dysfunction (PISD) completed ratings o f their sexual functioning pre- and posttreatment, Both women and men repor ted significant improvements (p = .001) in all domains of sexual functionin g, with 88% reporting improvement in overall sexual satisfaction. Significa nt improvements were reported regardless of psychotropic medication type. H owever, patients taking selective serotonin re-uptake inhibitors reported l ess improvement in arousal, libido, and overall sexual satisfaction than di d other patients, whereas patients taking benzodiazepines reported signific antly more improvement in libido and overall sexual satisfaction. Oral sild enafil may be an effective treatment for PISD.