We report the case of a woman with clinical and histopathological features
of reticular erythematous mucinosis syndrome (REM) who six years later deve
loped diagnostic criteria for systemic lupus erythematosus (SLE). Two biops
ies performed at the same area initially showed mucin dermal deposits and f
urther development of characteristic dermo-epidermal changes of lupus eryth
ematosus.
Our findings suggest that SLE may present with an REM-like condition.