The expression pattern of a novel Deltex homologue during chicken embryogenesis

Authors
Frolova, E Beebe, D
Citation
E. Frolova et D. Beebe, The expression pattern of a novel Deltex homologue during chicken embryogenesis, MECH DEVEL, 92(2), 2000, pp. 285-289
Citations number
17
Categorie Soggetti
Cell & Developmental Biology
Journal title
MECHANISMS OF DEVELOPMENT
ISSN journal
09254773 → ACNP
Volume
92
Issue
2
Year of publication
2000
Pages
285 - 289
Database
ISI
SICI code
0925-4773(200004)92:2<285:TEPOAN>2.0.ZU;2-P
Abstract
We isolated a partial cDNA encoding a novel chicken homologue of human Delt ex (DTX1), a member of the Notch signaling pathway. The cDtx2 sequence show ed higher homology to KIAA0937 protein (92% identical) than to DTX1 (68% id entical), cDtx2 is expressed widely in the epiblast at stage 4. Later in de velopment it is expressed in many neural and sensory structures, such as ne ural tube, migrating neural crest cells, epidermal placodes, cranial gangli a, and the optic and otic vesicles. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.