Recent advancements in functional neuroimaging have furthered our understan
ding of the normal and pathological brain. These non-invasive imaging modal
ities have allowed us to study the human brain in vivo. Concurrently, the r
evival of neurostimulation in the treatment of pain, movement disorders, an
d epilepsy has allowed the synergistic combination of these two technologie
s. Several studies focusing on the use of functional imaging in patients wi
th implanted neurostimulation devices are reviewed. The anticipated roles o
f these two disciplines are discussed.