Treatment of multifocal motor neuropathy with interferon-beta 1A

Nine patients with multifocal motor neuropathy who had previously responded favorably to TV immunoglobulins (IVIg) were treated with interferon-pla. M uscle strength and disability were evaluated. In six patients there was no effect of treatment. Four patients deteriorated in such a way that IVIg had to be restarted during the study, Three patients showed an improvement tha t was more pronounced than on IVIg. These patients had a shorter disease du ration and were less affected clinically and electrophysiologically than th ose who did not respond.