Molecular mechanisms in bile formation

Authors
Meier, PJ Stieger, B
Citation
Pj. Meier et B. Stieger, Molecular mechanisms in bile formation, NEWS PHYSL, 15, 2000, pp. 89-93
Citations number
15
Categorie Soggetti
Physiology
Journal title
NEWS IN PHYSIOLOGICAL SCIENCES
ISSN journal
08861714 → ACNP
Volume
15
Year of publication
2000
Pages
89 - 93
Database
ISI
SICI code
0886-1714(200004)15:<89:MMIBF>2.0.ZU;2-R
Abstract
Active canalicular secretion of bile salts and non-bile salt organic anions represents the major driving force of hepatic bile formation. The most imp ortant carriers involved have now been cloned on both the basolateral and c analicular sides of hepatocytes. Elucidation of their structure, transport properties, and regulation is an important step forward in the ultimate und erstanding of the molecular physiology of bile formation.