This paper reviews recent work on a new geometric object called a bundle ge
rbe and discusses some new examples arising in quantum field theory. One ap
plication is to an Atiyah-Patodi-Singer index theory construction of the bu
ndle of fermionic Fock spaces parameterized by vector potentials in odd spa
ce dimensions and a proof that this leads in a simple manner to the known S
chwinger terms (Mickelsson-Faddeev cocycle) for the gauge group action. Thi
s gives an explicit computation of the Dixmier-Douady class of the associat
ed bundle gerbe. The method also works in other cases of fermions in extern
al fields (external gravitational field, for example) provided that the APS
theorem can be applied; however, we have worked out the details only in th
e case of vector potentials. Another example, in which the bundle gerbe cur
vature plays a role, arises from the WZW model on Riemann surfaces. A furth
er example is the "existence of string structures" question. We conclude by
showing how global Hamiltonian anomalies fit within this framework.