The prevalence of atopic disease in Switzerland is 15-20%. About 30% of the
se patients have perennial symptoms and a substantial proportion are allerg
ic to house-dust mite proteins. If absolute air humidity is lower than 7.0
g water per kg air, house-dust mites will not proliferate. This is why the
occurrence of house-dust mites varies between different regions. About half
of the patients with allergy to house-dust mites complain of rhinitis, a q
uarter of asthma and a quarter of asthma and rhinitis. The diagnosis is usu
ally by history, skin prick tests and if necessary provocation. Therapy inc
ludes allergen avoidance (reduction of air humidity in dwellings by ventila
tion, encasing of mattresses and bedding), medication (mainly topical corti
costeroids) and specific immunotherapy.