Laparoscopic cholecystectomy is associated with a significant risk of gallb
ladder perforations with bile and stone spillage. The retrieval of dropped
stones is sometimes impossible, and intraperitoneally retained stones can b
e the source of serious complications, such as inflammatory masses or absce
sses. The authors describe a patient in whom a large retroperitoneal absces
s developed as a result of missed stone fragments during cholecystectomy. A
lthough several cases of intraperitoneal abscess have been reported in the
literature, retroperitoneal collection is very uncommon. Crushed and infect
ed stones seem to be the essential prerequisite for abscess formation. Ther
efore, every attempt should be made to avoid stone spillage and intra-abdom
inally retained stones. Conversion to open surgery has to be considered in
the presence of adverse factors, such as primary acute cholecystitis or cho
lecystitis induced by previous sphincterotomy, or bilirubinate stones belie
ved to be infected. Abdominal abscess treatment requires removal of missed
stones by surgical incision or new laparoscopic procedure because simple pe
rcutaneous drainage is usually unsuccessful.