Preparation and catalytic enantioselective reactions of C-3-symmetric tris(oxazoline)s derived from Kemp's triacid

Kemp's triacid was elaborated to optically pure tris(beta-hydroxylamide)s a nd tris(oxazoline)s. The resulting C-3-symmetric compounds were used in die thylzinc additions to benzaldehyde and allylic oxidations of cyclopentene, based on Kharash reaction conditions, to give the corresponding products in good chemical yields and moderate enantioselectivities.