Synthesis of new chiral aziridinoalcohols

Citation
L. Orea et al., Synthesis of new chiral aziridinoalcohols, SYN COMMUN, 30(7), 2000, pp. 1303-1309
Citations number
15
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
30
Issue
7
Year of publication
2000
Pages
1303 - 1309
Database
ISI
SICI code
0039-7911(2000)30:7<1303:SONCA>2.0.ZU;2-2
Abstract
Diasteromerically and enantiomerically pure aziridinoalcohols 4, 5, 6 and 7 were obtained from the reaction of racemic methyl 2, 3-dibromopropionate 1 with R and S-(2-phenylglycinol) 2 and 3 respectively. The products were se parated via flash chromatography on silica gel in good yield.