Studies on chromium(0)-mediated three component cycloaddition reactions

Authors
Rigby, JH Heap, CR Warshakoon, NC
Citation
Jh. Rigby et al., Studies on chromium(0)-mediated three component cycloaddition reactions, TETRAHEDRON, 56(15), 2000, pp. 2305-2311
Citations number
33
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
56
Issue
15
Year of publication
2000
Pages
2305 - 2311
Database
ISI
SICI code
0040-4020(20000407)56:15<2305:SOCTCC>2.0.ZU;2-4
Abstract
A novel chromium(0)-promoted three-component alkyne-triene higher-order cyc loaddition process is presented. The transformation features tethered alkyn es participating in a tandem [6 pi + 2 pi], [6 pi + 2 pi] cycloaddition eve nt with cyclic trienes serving as the third reactant. Isomerically homogene ous products possessing five rings and six stereogenic centers are isolated from this reaction in good to excellent yield. (C) 2000 Elsevier Science L td. All rights reserved.