The asymmetric cyclohexenylation of 2,2-dimethyl-2,3-dihydrofuran

Authors
Hennessy, AJ Malone, YM Guiry, PJ
Citation
Aj. Hennessy et al., The asymmetric cyclohexenylation of 2,2-dimethyl-2,3-dihydrofuran, TETRAHEDR L, 41(13), 2000, pp. 2261-2264
Citations number
13
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
13
Year of publication
2000
Pages
2261 - 2264
Database
ISI
SICI code
0040-4039(20000327)41:13<2261:TACO2>2.0.ZU;2-O
Abstract
The palladium catalysed asymmetric cyclohexenylation of 2,2-dimethyl-2,3-di hydrofuran is described. Use of this substrate allowed for an easy and dire ct comparison of a range of ligands in this reaction. The ligands employed included BINAP and phosphinamines and enantioselectivities of up to 97% wer e obtained with tert-leucinol-derived diphenylphosphinoaryloxazolines. (C) 2000 Elsevier Science Ltd. All rights reserved.