NEW POLYHYDROXYSTEROIDS AND STEROID GLYCOSIDES FROM THE FAR-EAST STARFISH CERAMASTER PATAGONICUS

Two new polyhydroxysteroids and five new glycosides were isolated from the starfish Ceramaster patogonicus and their structures were elucida ted: 5 alpha-cholestane-3 beta,6 alpha,15 beta,16 beta,26-pentol, (22E )-5 alpha-cholest-22-ene-3 beta,6 alpha,8,15 alpha,24-pentol, (22E)-28 -O-[O-(2-O-methyl-beta-D-xylopyranosyl)-(1 --> 2)-beta-D-galactofurano syl]-24-hydroxymethyl-5 alpha-cholest-22-ene-3 beta,4 beta,6 alpha,8,1 5 beta,16 beta,28-heptol (ceramasteroside C-1), -28-O-[O-(2,4-di-O-met hyl-beta-D-xylopyranosyl)-(1 --> 2)-beta-D-galactofuranosyl]-24-hydrox ymethyl-5 alpha-cholest-22-ene-3 beta,6 alpha,8,15 beta,16 beta,28-hex ol (ceramasteroside C-2), (22E)-28-O-[O-(2-O-methyl-beta-D-xylopyranos yl)-(1 --> 2) beta-D-galactofuranosyl]-24-hydroxymethyl-5 alpha-choles t-22-ene-3 beta,6 alpha,8,15 beta,16 beta,28-hexol (ceramasteroside C- 3) (22E)-28-O-[O-(2-O-methyl-beta-D-xylopyranosyl)-(1 --> 2)-beta-D-ga lactofuranosyl]-24-methyl-5 alpha-cholest-22-ene-3 beta,4 beta,6 alpha ,8,15 beta,26-hexol (ceramasteroside C-4), and (22E)-28-O-[O-(2-O-meth yl-beta-D-xylopyranosyl)-(1 --> 2)-beta-D-xylopyranosyl]-5 alpha-chole st-22-ene-3 beta,6 alpha,8,15 beta,24-pentol (ceramasteroside C-5)). T hree known polyhydroxysteroids (24-methylene-5 alpha-cholestane-3 beta ,6 alpha,8,15 beta,16 beta,26-hexol, 5 alpha-cholestane-3 beta,6 alpha ,8,15 beta,16 beta,26-hexol, and 5 alpha-cholestane-3 beta,6 beta,15 a lpha,16 beta,26-pentol) were also isolated.