Recent data on the expression of several homeobox genes in the embryonic te
lencephalon of mammals, birds and reptiles support the homology of a part o
f the avian pallium, named the Wulst, and at least the more-medial and supe
rior parts of mammalian neocortex. This conclusion is also supported by pre
vious embryological, topological and hodological data, Furthermore, new evi
dence on the connections and electrophysiological properties of specific su
bfields within the avian Wulst, and on the thalamic territories that projec
t to these fields, supports the more-specific conclusion that a primary vis
ual area-and a primary somatosensory-somatomotor area are present in the av
ian Wulst; these areas are likely to be homologous to their counterparts in
mammals. In spite of this, developmental, morphological and comparative ev
idence indicate that some structural and physiological traits that appear t
o be similar in the Wulst and neocortex (such as the lamination or binocula
rity) evolved independently in birds and mammals.