CA 125: A clinically useful tumor marker in the management of colorectal carcinoma metastatic to the liver in patients with normal carcinoembryonic antigen

Authors
Mavligit, GM Estrov, Z
Citation
Gm. Mavligit et Z. Estrov, CA 125: A clinically useful tumor marker in the management of colorectal carcinoma metastatic to the liver in patients with normal carcinoembryonic antigen, AM J CL ONC, 23(2), 2000, pp. 213-215
Citations number
6
Categorie Soggetti
Oncology
Journal title
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
ISSN journal
02773732 → ACNP
Volume
23
Issue
2
Year of publication
2000
Pages
213 - 215
Database
ISI
SICI code
0277-3732(200004)23:2<213:C1ACUT>2.0.ZU;2-F
Abstract
Two patients with colon carcinoma metastatic to the liver had normal plasma carcinoembryonic antigen (CEA) levels (<1.0 ng/ml) but elevated CA 125 lev els. Treatment of the metastatic disease with chemotherapy, plus surgery in one case, led to declines in the CA. 125 levels. These decreases were asso ciated with tumor regression, as confirmed by clinical and radiologic evide nce. These findings lead us to conclude that the measurement of CA 125 for patients with normal CEA levels is useful in the management of colorectal c arcinoma.